Disruption of microtubule-dependent transport triggers accumulation and oligomerization of TDP-43 in the cytoplasm, leading to neurodegeneration in ALS.
Disruption of microtubule-dependent transport triggers accumulation and oligomerization of TDP-43 in the cytoplasm, leading to neurodegeneration in ALS.
复制标题
微管依赖性运输的破坏会触发细胞质中 TDP-43 的积累和寡聚化,导致 ALS 中的神经变性。
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发表时间:
2013
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通讯作者:
Nagai Y.
中科院分区:
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作者:
Fujikake N.;et al.;Nagai Y.