New, faster, image-based scatter correction for 3D PET

New, faster, image-based scatter correction for 3D PET
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DOI:
10.1109/23.873020
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发表时间:
2000-08-01
影响因子:
1.8
通讯作者:
Watson, CC
Watson, CC
中科院分区:
工程技术3区
文献类型:
--
作者:
Watson, CC

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我们报告一个新的数值实现的单散射模拟散射校正算法的三维PET。其相对于原始实现的主要优点是,它是一个更快的计算,目前需要不到30秒的执行时间,每个床位置的成人胸部,从而使临床全身散射校正更实用。新的代码运行在单处理器工作站CPU上,而不是矢量处理器阵列上,这使得它具有高度的可移植性。它是模块化的,独立于任何特定的重建代码。计算的散射贡献现在相对于发射图像进行了内在缩放,并且当所有活动都包含在视场内时,不再需要归一化到正弦图中的散射尾部,从而使其对噪声更加鲁棒。新算法已在体模和人体胸部研究中针对原始代码进行了验证。最初的手段表明,散射校正可以准确地执行后,而不是之前,无论是3D重投影或傅立叶重组。一些证据表明,单散射运营商,当应用到一个未校正的发射图像提供了合理的补偿多次散射。
We report on a new numerical implementation of the single-scatter simulation scatter correction algorithm for 3D PET. Its primary advantage over the original implementation is that it is a much faster calculation, currently requiring less than 30 sec execution time per bed position for an adult thorax, thus making clinical whole-body scatter correction more practical. The new code runs on a single processor workstation CPU instead of a vector processor array, making it highly portable. It is modular and independent of any particular reconstruction code. The computed scatter contribution is now intrinsically scaled relative to the emission image and no longer requires normalization to the scatter tails in the sinogram when all activity is contained within the field of view, making it more robust against noise. The new algorithm has been verified against the original code on both phantom and human thorax studies. Initial resorts indicate that scatter correction may be accurately performed following, instead of prior to, either 3D reprojection or Fourier rebinning. Some evidence is presented that the single-scatter operator, when applied to an uncorrected emission image provides reasonable compensation for multiple scatter.