Changes in visual receptive fields with microstimulation of frontal cortex
Changes in visual receptive fields with microstimulation of frontal cortex
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DOI：
10.1016/j.neuron.2006.05.010
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发表时间：
2006-06-01
期刊：
影响因子：
16.2
通讯作者：
Moore, Tirin
中科院分区：
文献类型：
--
作者：
Armstrong, Katherine M.;Fitzgerald, Jamie K.;Moore, Tirin
注意对视觉皮层神经元的影响已被描述为其对感受野（RFs）结构的影响，其中多种刺激竞争驱动神经反应和最终行为。我们刺激了被动注视猴子的额叶视野（FEF），并产生了V4反应的变化，类似于已知的自愿注意的影响。阈下FEF刺激增强了RF内特定位置的视觉反应，并改变了成对RF刺激之间的相互作用，使那些与激活FEF部位一致的刺激物更受青睐。因此，我们可以影响哪个刺激驱动单个V4神经元的反应。这些结果表明，参与扫视准备的空间信号被用来在视觉皮层神经元的RFs中隐蔽地选择多种刺激。
The influence of attention on visual cortical neurons has been described in terms of its effect on the structure of receptive fields (RFs), where multiple stimuli compete to drive neural responses and ultimately behavior. We stimulated the frontal eye field (FEF) of passively fixating monkeys and produced changes in V4 responses similar to known effects of voluntary attention. Subthreshold FEF stimulation enhanced visual responses at particular locations within the RF and altered the interaction between pairs of RF stimuli to favor those aligned with the activated FEF site. Thus, we could influence which stimulus drove the responses of individual V4 neurons. These results suggest that spatial signals involved in saccade preparation are used to covertly select among multiple stimuli appearing within the RFs of visual cortical neurons.