Java application for cytoskeleton filament characterization (JACFC)
Java application for cytoskeleton filament characterization (JACFC)
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DOI：
10.1016/j.simpa.2021.100072
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发表时间：
2021-05-01
期刊：
影响因子：
--
通讯作者：
Marucho, Marcelo
中科院分区：
文献类型：
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作者：
Marucho, Marcelo
JACFC 是一个 Java Web 应用程序 (http://neuronanobiophysicals.utsa.edu/)，为该领域的专家和非专家提供合适的工具，用于阐明在不同分子（野生型、异构体、突变体）和环境（生理和病理）条件下调节微管和肌动蛋白丝的电信号传播、稳定性和束形成的分子机制。这一认识可能揭示细胞骨架丝在神经元活动中的潜在作用，包括分子水平的信息处理和神经再生。对生物纳米线聚电解质特性的分子理解对于开发具有生物技术应用的可靠性、高性能小型设备（例如生物纳米传感器和计算生物纳米处理器）也至关重要。
JACFC is a Java web application (http://neuronanobiophysics.utsa.edu/) that provides both experts and non-experts in the field suitable tools for elucidating the molecular mechanisms modulating the electrical signal propagation, stability, and bundle formation of microtubules and actin filaments under different molecular (wild type, isoforms, mutants) and environmental (physiological and pathological) conditions. This acknowledgment might reveal the potential role of cytoskeleton filaments in neuronal activities, including molecular-level processing of information and neural regeneration. Molecular understanding of the polyelectrolyte properties of bionanowires, is also crucial for development of reliability, highly functioning small devices with biotechnological applications such as bionanosensors and computing bionanoprocessors.