Genetic testing of African Americans for susceptibility to inherited cancers: Use of focus groups to determine factors contributing to participation
Genetic testing of African Americans for susceptibility to inherited cancers: Use of focus groups to determine factors contributing to participation
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DOI：
10.1300/j077v18n02_01
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发表时间：
2000-01-01
影响因子：
2.1
通讯作者：
Olopade, OI
中科院分区：
文献类型：
--
作者：
Matthews, AK;Cummings, S;Olopade, OI
BRCA1和BRCA2基因的鉴定为乳腺癌、卵巢癌、结肠癌或前列腺癌的高危人群提供了了解他们是否在遗传上易患这些疾病的机会。芝加哥大学医学中心的医学系有一个项目，为有这些癌症家族史的人提供基因检测。然而，非裔美国人不像欧裔美国人那样参加基因检测。因此，进行焦点小组研究，以了解更多影响非裔美国人参与基因检测的因素。研究结果表明，有几个因素影响他们的参与，包括对癌症生存能力的认识以及对基因检测作用的认识不足。本文讨论了这些因素，并提供了具体的建议，以改善非裔美国人获得和响应基因检测。
Identification of the genes BRCA1 and BRCA2 offers individuals at high risk for breast, ovarian, colon, or prostate cancer the opportunity to learn if they are genetically predisposed to these diseases. The department of Medicine at the University of Chicago Medical Center has a program that provides genetic testing for people with a family history of these cancers. However, African Americans do not participate in genetic testing at the same rate European Americans do. Thus, focus groups were conducted to learn more about the factors influencing the participation of African Americans in genetic testing. The findings indicated that several factors influence their participation, including perceptions about cancer survivability and lack of awareness about the role of genetic testing. The article discusses these factors and provides specific recommendations for improving African Americans' access and response to genetic testing.