Going viral: Designing bioactive surfaces with bacteriophage

Going viral: Designing bioactive surfaces with bacteriophage
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DOI:
10.1016/j.colsurfb.2014.05.036
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发表时间:
2014-12-01
影响因子:
5.8
通讯作者:
Tufenkji, Nathalie
Tufenkji, Nathalie
中科院分区:
工程技术2区
文献类型:
--
作者:
Hosseinidoust, Zeinab;Olsson, Adam U.;Tufenkji, Nathalie

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噬菌体功能化的生物活性表面是功能材料,可用作医疗应用中的抗菌表面(例如,留置医疗设备或伤口敷料)或用作细菌捕获和检测的生物传感器。尽管提供了巨大的潜力,但设计高效的噬菌体功能化生物活性表面仍受到许多挑战的阻碍。这篇综述概述了该领域的知识现状,并提出了技术前景和挑战的批判性视角。 (C) 2014 Elsevier B.V. 保留所有权利。
Bacteriophage-functionalized bioactive surfaces are functional materials that can be used as antimicrobial surfaces in medical applications (e.g., indwelling medical devices or wound dressings) or as biosensors for bacterial capture and detection. Despite offering immense potential, designing efficient phage-functionalized bioactive surfaces is hampered by a number of challenges. This review offers an overview of the current state of knowledge in this field and presents a critical perspective of the technological promises and challenges. (C) 2014 Elsevier B.V. All rights reserved.