The Long-Term Effects of Mindfulness-Based Cognitive Therapy as a Relapse Prevention Treatment for Major Depressive Disorder
The Long-Term Effects of Mindfulness-Based Cognitive Therapy as a Relapse Prevention Treatment for Major Depressive Disorder
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DOI：
10.1017/s135246581000010x
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发表时间：
2010-10-01
影响因子：
1.8
通讯作者：
Denson, Linley A.
中科院分区：
文献类型：
--
作者：
Mathew, Kate L.;Whitford, Hayley S.;Denson, Linley A.
背景：正念认知疗法（MBCT）是一种预防抑郁症复发的治疗方法。方法：一项对39名参与者进行的观察性临床审计，使用标准化的抑郁（BDI-II）、反刍（RSS）和正念（MAAS）指标，探讨了正念认知疗法的长期影响。结果：正念认知疗法与治疗前后抑郁症的显著减少相关。随着时间的推移，收益保持不变（第1组，1-12个月，p = 0.002;第2组，13-24个月，p = 0.001;第3组，25-34个月，p = 0.04）。第3组的抑郁评分确实开始恶化，但仍在BDI-II的轻度范围内。治疗变量，如参加“助推器”会议和持续的正念练习与更好的抑郁症结果相关（分别为p = .003和p = .03）。沉思和正念注意力之间有很强的负相关（p <0.001），这与正念认知疗法疗效中的元认知机制一致。结论：这表明，持续的正念认知疗法的技能和实践可能是重要的复发预防在较长的时间。建议对MBCT机制进行更大规模的随机研究，并进行更长时间的随访。
Background: Mindfulness-based Cognitive Therapy (MBCT) is a relapse prevention treatment for major depressive disorder. Method: An observational clinical audit of 39 participants explored the long-term effects of MBCT using standardized measures of depression (BDI-II), rumination (RSS), and mindfulness (MAAS). Results: MBCT was associated with statistically significant reductions in depression from pre to post treatment. Gains were maintained over time (Group 1, 1-12 months, p = .002; Group 2, 13-24 months, p = .001; Group 3, 25-34 months, p = .04). Depression scores in Group 3 did begin to worsen, yet were still within the mild range of the BDI-II. Treatment variables such as attendance at " booster" sessions and ongoing mindfulness practice correlated with better depression outcomes (p = .003 and p = .03 respectively). There was a strong negative correlation between rumination and mindful attention (p < .001), consistent with a proposed mechanism of metacognition in the efficacy of MBCT. Conclusion: It is suggested that ongoing MBCT skills and practice may be important for relapse prevention over the longer term. Larger randomized studies of the mechanisms of MBCT with longer follow-up periods are recommended.