Pomegranate juice is potentially better than apple juice in improving antioxidant function in elderly subjects
Pomegranate juice is potentially better than apple juice in improving antioxidant function in elderly subjects
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DOI：
10.1016/j.nutres.2007.12.001
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发表时间：
2008-02-01
影响因子：
4.5
通讯作者：
Jiang, Yugang
中科院分区：
文献类型：
--
作者：
Guo, Changjiang;Wei, Jingyu;Jiang, Yugang
在本研究中，招募了26名老年受试者，并随机分为2组，即苹果（抗氧化能力低）和石榴（抗氧化能力高）组，每天饮用250 mL果汁，持续4周。测定血浆抗氧化能力、抗氧化酶活性、抗坏血酸、维生素E、还原型谷胱甘肽、丙二醛、氧化型低密度脂蛋白和羰基化合物含量及单个核细胞DNA损伤程度。收集尿液样本用于测定8-羟基-2 '-脱氧鸟苷含量。每天食用石榴汁后，血浆抗氧化能力增加，血浆羰基含量降低。相比之下，苹果汁消费呈现出对老年人的抗氧化功能的影响不太显着。结论是，每天饮用石榴汁可能比苹果汁更能改善老年人的抗氧化功能。由于血浆抗坏血酸，维生素E，还原型谷胱甘肽含量在本研究中的2组之间没有显着差异，酚类物质可能是石榴汁中所含的功能成分，占观察。(c)2008年爱思唯尔公司All rights reserved.
In the present study, 26 elderly subjects were recruited and randomly divided into 2 groups, that is, apple (low in antioxidant capacity) and pomegranate (high in antioxidant capacity) groups, and 250 mL of juice was consumed daily for 4 weeks. Changes in plasma antioxidant capacity, activity of antioxidant enzymes, contents of ascorbic acid, vitamin E, reduced glutathione, malondialdehyde, oxidized low-density lipoprotein and carbonyls, and the degree of DNA damage in mononuclear blood cells were measured. Urine samples were collected for determination of 8-hydroxy-2 '-deoxyguanosine content. Increased plasma antioxidant capacity and decreased plasma carbonyl content were demonstrated after daily consumption of pomegranate juice. In comparison, apple juice consumption presented a less significant effect on antioxidant function in elderly subjects. It is concluded that daily consumption of pomegranate juices is potentially better than apple juice in improving antioxidant function in the elderly. Because the plasma ascorbic acid, vitamin E, and reduced glutathione contents did not differ significantly between the 2 groups in this study, the phenolics may be the functional components contained in pomegranate juice that accounted for the observations. (c) 2008 Elsevier Inc. All rights reserved.