Electronic nicotine delivery systems: is there a need for regulation?
Electronic nicotine delivery systems: is there a need for regulation?
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DOI：
10.1136/tc.2010.037259
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发表时间：
2011-01-01
期刊：
影响因子：
5.2
通讯作者：
Talbot, Prue
中科院分区：
文献类型：
--
作者：
Trtchounian, Anna;Talbot, Prue
目的电子尼古丁输送系统（ENDS）旨在将尼古丁输送到吸烟者的肺部。对五个品牌的ENDS进行了设计特点、标签的准确性和清晰度以及随产品或制造商网站提供的说明书和相关印刷材料的质量评估。方法从网上采购ENDS，对其各项参数进行分析。结果虽然不同品牌的ENDS基本设计相似，但具体设计特征差异很大。装在药筒储液器中的液体很容易从大多数品牌中泄漏出来，而且在不接触含尼古丁液体的情况下很难组装或拆卸ENDS。有两个品牌的设计有助于减轻这个问题。墨盒的标签非常差；一些盒式包装的标签优于盒式标签。一般来说，替换盒的包装比包装或盒的标签更好，但大多数包装缺乏盒的内容和警告信息，有时包装上有令人困惑的信息。使用过的墨盒含有液体，网站或使用手册中没有充分说明如何处理含尼古丁的墨盒。订单有时会被错误地填写，安全功能也不总是正常工作。印刷和互联网材料通常包含目前没有科学支持的信息或主张。设计缺陷、缺乏足够的标签以及对质量控制和健康问题的担忧表明，监管机构应考虑将ENDS从市场上移除，直到其安全性得到充分评估。
Purpose Electronic nicotine delivery systems (ENDS) purport to deliver nicotine to the lungs of smokers. Five brands of ENDS were evaluated for design features, accuracy and clarity of labelling and quality of instruction manuals and associated print material supplied with products or on manufacturers' websites.Methods ENDS were purchased from online vendors and analysed for various parameters.Results While the basic design of ENDS was similar across brands, specific design features varied significantly. Fluid contained in cartridge reservoirs readily leaked out of most brands, and it was difficult to assemble or disassemble ENDS without touching nicotine-containing fluid. Two brands had designs that helped lessen this problem. Labelling of cartridges was very poor; labelling of some cartridge wrappers was better than labelling of cartridges. In general, packs of replacement cartridges were better labelled than the wrappers or cartridges, but most packs lacked cartridge content and warning information, and sometimes packs had confusing information. Used cartridges contained fluid, and disposal of nicotine-containing cartridges was not adequately addressed on websites or in manuals. Orders were sometimes filled incorrectly, and safety features did not always function properly. Print and internet material often contained information or made claims for which there is currently no scientific support.Conclusions Design flaws, lack of adequate labelling and concerns about quality control and health issues indicate that regulators should consider removing ENDS from the market until their safety can be adequately evaluated.