The isoenzymes of mammalian hexokinase: tissue specificity and in vivo decline.

The isoenzymes of mammalian hexokinase: tissue specificity and in vivo decline.
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哺乳动物己糖激酶的同工酶:组织特异性和体内衰退。

DOI:
10.1007/978-1-4684-5985-2_25
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发表时间:
1991
影响因子:
--
通讯作者:
Piomelli,S
Piomelli,S
中科院分区:
医学4区
文献类型:
--
作者:
Murakami,K;Piomelli,S

文献摘要

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网织红细胞在成熟为红细胞(RBC)的过程中失去了大部分细胞器。红细胞在其120天的寿命期间仍然依赖于预先形成的酶机制,因为它不能合成蛋白质。这提供了一个很好的分子老化模型。
The reticulocyte loses most of its intracellular organelles during maturation into the red blood cell (RBC). The RBC remains dependent on the preformed enzymatic machinery throughout its 120 day life-span, as it is incapable of protein synthesis. This provides an excellent model of molecular aging.