Quality of life and a symptom cluster associated with breast cancer treatment-related lymphedema
Quality of life and a symptom cluster associated with breast cancer treatment-related lymphedema
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DOI：
10.1007/s00520-005-0810-y
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发表时间：
2005-11-01
影响因子：
3.1
通讯作者：
Ridner, SH
中科院分区：
文献类型：
--
作者：
Ridner, SH
目的：本研究的目的是比较乳腺癌幸存者之间的生活质量和症状谁已经开发和接受治疗的慢性水肿与那些谁没有开发水肿。患者和方法：横断面，混合方法设计包括64例乳腺癌幸存者水肿和64例乳腺癌幸存者没有水肿。定量评估的变量包括社会人口学信息、医疗数据、体重指数（BMI）、手臂细胞外液量、生活质量（QOL）以及身体和情绪症状。对于定性部分，水肿患者以书面形式回答问题：在过去的一周里，由于水肿，您还经历了哪些其他困难？结果：与无水肿的患者相比，有水肿的乳腺癌幸存者的生活质量较差。确定了一组症状，包括肢体感觉改变、对身体失去信心、体力活动减少、疲劳和心理困扰。肢体大小的感知影响累积症状的经验比客观手臂体积。定性数据显示多个生活质量，身体健康和心理问题。BMI与多种结局相关。结论：研究结果表明，目前的水肿治疗，虽然有益的，可能无法提供与水肿和补充干预措施相关的症状完全缓解。乳腺癌幸存者中存在水肿的患者生活质量较差，可能与未治疗的症状群有关。
Objectives: The aim of this study was to compare quality of life and symptoms between breast cancer survivors who have developed and undergone treatment for chronic lymphedema with those who have not developed lymphedema. Patients and methods: The cross-sectional, mixed-methods design included 64 breast cancer survivors with lymphedema and 64 breast cancer survivors without lymphedema. Variables assessed quantitatively included sociodemographic information, medical data, body mass index (BMI), arm extracellular fluid volume, quality of life (QOL), and physical and emotional symptoms. For the qualitative component, individuals with lymphedema responded in writing to the question: During the past week what other difficulties have you experienced because of your lymphedema? Results: Compared with those without lymphedema, breast cancer survivors with lymphedema reported poorer QOL. A symptom cluster that included alteration in limb sensation, loss of confidence in body, decreased physical activity, fatigue, and psychological distress was identified. Perception of limb size influenced the cumulative symptom experience more than objective arm volume. Qualitative data revealed multiple QOL, physical health, and psychological concerns. BMI correlated with multiple outcomes. Conclusions: Findings suggest that current lymphedema treatments, although beneficial, may not provide complete relief of symptoms associated with lymphedema and complementary interventions are needed. The poorer QOL in breast cancer survivors with lymphedema may relate to the presence of an untreated symptom cluster.