Antibiotic resistance: Consequences of inaction
Antibiotic resistance: Consequences of inaction
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DOI：
10.1086/321837
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发表时间：
2001-09-15
影响因子：
11.8
通讯作者：
Levy, SB
中科院分区：
文献类型：
--
作者：
Levy, SB
细菌耐药性给全世界的临床医生提出了治疗难题。这些警告很久以前就存在了，但很少有人理会它们。因此，一个新出现的问题已经发展成为一场危机。耐药性是一种生态现象，源于细菌对抗生素的广泛使用及其在环境中的存在的反应。在确定不采取行动对当前和未来公共卫生的后果的同时，我们必须努力弥补过去不采取行动的不足。通过在地方层面改善抗生素的使用和减少耐药基因的频率，我们可以在全球范围内扭转耐药性问题。
Bacterial resistance presents therapeutic dilemmas to clinicians worldwide. The warnings were there long ago, but too few people heeded them. Thus an emerging problem has grown to a crisis. Resistance is an ecological phenomenon stemming from the response of bacteria to the widespread use of antibiotics and their presence in the environment. While determining the consequences of inaction on the present and future public health, we must work to remedy the lack of action in the past. By improving antibiotic use and decreasing resistance gene frequency at the local levels, we can move towards reversing the resistance problem globally.