New cytotoxic isomalabaricane-type sesterterpenes from the New Caledonian marine sponge Rhabdastrella globostellata

New cytotoxic isomalabaricane-type sesterterpenes from the New Caledonian marine sponge Rhabdastrella globostellata
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DOI:
10.1016/s0040-4039(00)00345-2
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发表时间:
2000-04-22
影响因子:
1.8
通讯作者:
Guyot, M
Guyot, M
中科院分区:
化学4区
文献类型:
--
作者:
Bourguet-Kondracki, ML;Longeon, A;Guyot, M

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从新喀里多尼亚海绵Rhabdastrellagrobostellata中分离出4个新的细胞毒性isomalabaricane二倍半萜,aurorals 1 - 4。它们的结构通过光谱数据包括一维和二维技术确定。发现这些化合物对KB细胞表现出细胞毒性活性。(C)2000爱思唯尔科技有限公司版权所有。
Four new cytotoxic isomalabaricane sesterterpenes, aurorals 1-4, have been isolated from the New Caledonian marine sponge Rhabdastrella globostellata. Their structures were established by spectroscopic data including 1D and 2D techniques. These compounds were found to exhibit cytotoxic activity on KB cells. (C) 2000 Elsevier Science Ltd. All rights reserved.