Platelets from HIV-infected individuals on antiretroviral drug therapy with poor CD4+ T cell recovery can harbor replication-competent HIV despite viral suppression
Platelets from HIV-infected individuals on antiretroviral drug therapy with poor CD4+ T cell recovery can harbor replication-competent HIV despite viral suppression
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DOI：
10.1126/scitranslmed.aat6263
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发表时间：
2020-03-18
影响因子：
17.1
通讯作者：
Bomsel, Morgane
中科院分区：
文献类型：
--
作者：
Real, Fernando;Capron, Claude;Bomsel, Morgane
除了止血之外，人血小板还具有多种免疫功能，并在体外与包括HIV在内的感染性病原体相互作用。在此，我们报告了接受联合抗逆转录病毒药物治疗（ART）的HIV感染者的血小板与低血CD4 + T细胞计数（
In addition to hemostasis, human platelets have several immune functions and interact with infectious pathogens including HIV in vitro. Here, we report that platelets from HIV-infected individuals on combined antiretroviral drug therapy (ART) with low blood CD4(+) T cell counts (