Inverse association between dietary habits with high total antioxidant capacity and prevalence of frailty among elderly Japanese women: A multicenter cross-sectional study
Inverse association between dietary habits with high total antioxidant capacity and prevalence of frailty among elderly Japanese women: A multicenter cross-sectional study
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DOI：
10.1007/s12603-014-0556-7
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发表时间：
2014-12-01
影响因子：
5.8
通讯作者：
Sasaki, S.
中科院分区：
文献类型：
--
作者：
Kobayashi, S.;Asakura, K.;Sasaki, S.
旨在检查日本老年女性高总抗氧化能力 (TAC) 的饮食习惯与虚弱之间的关系。横断面多中心研究。日本 47 个都道府县中的 35 个。2121 名 65 岁及以上饮食学生的祖母或熟人。使用经过验证的简短型自填式饮食史调查问卷计算饮食 TAC 和食物摄入量。每种食物的 TAC 值使用四种不同的测定法进行分配：血浆铁还原能力 (FRAP)、氧自由基吸收能力 (ORAC)、Trolox 等效抗氧化能力 (TEAC) 和总自由基捕获抗氧化参数 (TRAP)。虚弱被定义为存在以下四个组成部分中的三个或更多：缓慢和虚弱（两分）、疲惫、体力活动少和无意的体重减轻。虚弱的受试者人数为 486 人（23%）。与最低五分位数相比，最高五分位数虚弱的多变量调整 OR（95% CI）分别为：FRAP 为 0.35（0.24，0.53），ORAC 为 0.35（0.23，0.52），TEAC 为 0.40（0.27，0.60），TRAP 为 0.41（0.28，0.62）。有助于饮食 TAC 的绿茶、咖啡、蔬菜和水果的摄入量也与较低的虚弱几率相关（多变量调整 OR 的范围：蔬菜为 0.47，绿茶为 0.77），尽管比值比不如饮食 TAC 显着。高 TAC 的饮食习惯与日本老年女性虚弱的负相关性强于所检查的个别食物。
To examine the association of dietary habits with high total antioxidant capacity (TAC) with frailty among elderly Japanese women.Cross-sectional multicenter study.Thirty-five of 47 prefectures in Japan.2121 grandmothers or acquaintances of dietetic students aged 65 and older.Dietary TAC and food intakes were calculated using a validated brief-type self-administered diet history questionnaire. The TAC value of each food was assigned using four different assays, ferric reducing ability of plasma (FRAP), oxygen radical absorbance capacity (ORAC), Trolox equivalent antioxidant capacity (TEAC), and total radical-trapping antioxidant parameter (TRAP). Frailty was defined as the presence three or more of the following four components: slowness and weakness (two points), exhaustion, low physical activity, and unintentional weight loss.The number of subjects with frailty was 486 (23%). Multivariate adjusted ORs (95% CI) for frailty in the highest compared to the lowest quintile were 0.35 (0.24, 0.53) for FRAP, 0.35 (0.23, 0.52) for ORAC, 0.40 (0.27, 0.60) for TEAC, and 0.41 (0.28, 0.62) for TRAP. The intakes of green tea, coffee, vegetables, and fruits which contribute to dietary TAC were also associated with lower odds of frailty (the range of multivariate adjusted OR: 0.47 for vegetables to 0.77 for green tea), although the odds ratios were less marked than those of dietary TAC.Dietary habits with high TAC showed a stronger inverse association with frailty in elderly Japanese women than the individual foods examined.