Adiposity and human regional body temperature
Adiposity and human regional body temperature
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DOI：
10.3945/ajcn.2009.27567
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发表时间：
2009-11-01
影响因子：
7.1
通讯作者：
Yanovski, Jack A.
中科院分区：
文献类型：
--
作者：
Savastano, David M.;Gorbach, Alexander M.;Yanovski, Jack A.
背景资料：人类肥胖与产热增加有关;然而，皮下脂肪组织提供了一个绝缘层，阻止热量损失。为了维持正常体温，因此，肥胖个体必须增加他们的散热量。目的：目的是检验肥胖成年人手部散热区域的温度升高的假设。设计：肥胖[体重指数（kg/m2）>= 30]和正常体重（NW;体重指数= 18-25）成年人在静止的热中性条件下进行研究。使用摄入的遥测胶囊测量核心体温。通过红外热成像法测定右手第三指甲床和脐下1.5厘米区域腹部皮肤的温度。腹部皮肤温度也通过放置在突出的皮肤表面血管和相邻的非血管位置上的粘性热敏电阻来测量。各组进行了比较，年龄，性别，种族和室温作为协variated.Results协方差分析：核心温度之间没有显着差异23肥胖和13 NW参与者（P = 0.74）。然而，红外热像仪测量的手指甲床温度在肥胖受试者中显著高于NW受试者（33.9 6 +/- 0.7摄氏度与28.6 +/- 0.9摄氏度; P < 0.001）。相反，红外热成像测量的腹部皮肤温度在肥胖受试者中显著低于NW受试者（31.8 +/- 0.2摄氏度与32.8 +/- 0.3摄氏度; P = 0.02）。非血管腹部皮肤温度测量的热敏电阻也较低的肥胖subjects（P = 0.04）。结论：更大的皮下腹部脂肪组织在肥胖的成年人可以提供一个显着的绝缘层，钝腹部热传递。从手部释放的热量增加可以抵消身体肥胖区域的热量滞留，从而有助于维持肥胖患者的正常体温。该试验在clinicaltrials.gov上注册为NCT 00266500。美国临床营养杂志2009; 90：1124-31。
Background: Human obesity is associated with increased heat production; however, subcutaneous adipose tissue provides an insulating layer that impedes heat loss. To maintain normothermia, therefore, obese individuals must increase their heat dissipation.Objective: The objective was to test the hypothesis that temperature in a heat-dissipating region of the hand is elevated in obese adults.Design: Obese [body mass index (in kg/m(2)) >= 30] and normal-weight (NW; body mass index = 18-25) adults were studied under thermoneutral conditions at rest. Core body temperature was measured by using ingested telemetric capsules. The temperatures of the third fingernail bed of the right hand and of abdominal skin from an area 1.5 cm inferior to the umbilicus were determined by using infrared thermography. Abdominal skin temperatures were also measured via adhesive thermistors that were placed over a prominent skin-surface blood vessel and over an adjacent nonvessel location. The groups were compared by analysis of covariance with age, sex, race, and room temperature as covariates.Results: Core temperature did not differ significantly between the 23 obese and 13 NW participants (P = 0.74). However, infrared thermography-measured fingernail-bed temperature was significantly higher in obese subjects than in NW subjects (33.9 6 +/- 0.7 degrees C compared with 28.6 +/- 0.9 degrees C; P < 0.001). Conversely, infrared thermography-measured abdominal skin temperature was significantly lower in obese subjects than in NW subjects (31.8 +/- 0.2 degrees C compared with 32.8 +/- 0.3 degrees C; P = 0.02). Nonvessel abdominal skin temperatures measured by thermistors were also lower in obese subjects (P = 0.04).Conclusions: Greater subcutaneous abdominal adipose tissue in obese adults may provide a significant insulating layer that blunts abdominal heat transfer. Augmented heat release from the hands may offset heat retention in areas of the body with greater adiposity, thereby helping to maintain normothermia in obesity. This trial was registered at clinicaltrials.gov as NCT00266500. Am J Clin Nutr 2009; 90: 1124-31.