CEREBRAL CARBOHYDRATE METABOLISM DURING ACUTE HYPOXIA AND RECOVERY 1
CEREBRAL CARBOHYDRATE METABOLISM DURING ACUTE HYPOXIA AND RECOVERY 1
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DOI：
10.1111/j.1471-4159.1972.tb01417.x
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发表时间：
1972-04
影响因子：
4.7
通讯作者：
T. Duffy;S. Nelson;O. H. Lowry
中科院分区：
文献类型：
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作者：
T. Duffy;S. Nelson;O. H. Lowry
翻译后摘要-ATP，ADP，AMP和磷酸肌酸的水平，四种氨基酸，和11个中间体的碳水化合物代谢在小鼠脑中测定：（1）不同程度的缺氧;（2）缺氧结合麻醉;和（3）从严重缺氧恢复。糖原减少，乳酸显着上升，在缺氧，但ATP和磷酸肌酸水平正常或接近正常，即使惊厥和呼吸衰竭出现迫在眉睫。
Abstract— The levels of ATP, ADP, AMP and phosphocreatine, of four amino acids, and of 11 intermediates of carbohydrate metabolism in mouse brain were determined after: (1) various degrees of hypoxia; (2) hypoxia combined with anaesthesia; and (3) recovery from severe hypoxia. Glycogen decreased and lactate rose markedly in hypoxia, but levels of ATP and phosphocreatine were normal or near normal even when convulsions and respiratory collapse appeared imminent.