Central sleep apnea is a predictor of cardiac readmission in hospitalized patients with systolic heart failure.
Central sleep apnea is a predictor of cardiac readmission in hospitalized patients with systolic heart failure.
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DOI：
10.1016/j.cardfail.2012.05.003
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发表时间：
2012-07
影响因子：
6
通讯作者：
Jarjoura, David
中科院分区：
文献类型：
--
作者：
Khayat, Rami;Abraham, William;Patt, Brian;Brinkman, Vincent;Wannemacher, Jacob;Porter, Kyle;Jarjoura, David
心力衰竭住院患者的再入院率很高。本研究旨在确定收缩性心力衰竭（SHF）患者因中枢性睡眠呼吸暂停（CSA）再入院的独立风险。患者在住院期间接受睡眠研究，并随访6个月以确定其心脏再入院率。共纳入784例连续患者。165例有CSA，139例无睡眠呼吸障碍（SDB）。其余患者患有阻塞性睡眠呼吸暂停（OSA）。CSA患者与无SDB患者相比，6个月心脏再入院率比为1.53（95% CI（1.1，2.2），p= 0.03）。该比率根据收缩功能、心肌病类型、年龄、体重、性别、糖尿病、冠心病、住院时间、入院钠、肌酐、血红蛋白、血压和出院药物进行调整。重度OSA也是再入院的独立预测因素，校正率比为1.49（p= 0.04）。在SDB对心力衰竭心脏再入院影响的首次评价中，CSA是6个月心脏再入院的独立风险因素。CSA的效应量超过了所有已知的心力衰竭再入院的预测因子。
Hospitalized heart failure patients have a high readmission rate. We sought to determine the independent risk due to central sleep apnea (CSA) of readmission in patients with systolic heart failure (SHF) Prospective observational cohort study of hospitalized patients with SHF. Patients underwent sleep studies during the hospitalization and were followed for 6 months to determine their rate of cardiac readmissions. 784 consecutive patients were included. 165 patients had CSA and 139 had no sleep disordered breathing (SDB). The remainder had obstructive sleep apnea (OSA). The rate ratio for 6 months cardiac readmissions was 1.53 (95% CI (1.1, 2.2), p=.03) in CSA patients compared to no SDB. This rate ratio is adjusted for systolic function, type of cardiomyopathy, age, weight, sex, diabetes, coronary disease, length of stay, admission sodium, creatinine, hemoglobin, blood pressure and discharge medications. Severe OSA was also an independent predictor of readmissions with an adjusted rate ratio of 1.49 (p=.04). In this first evaluation of the impact of SDB on cardiac readmissions in heart failure, CSA was an independent risk factor for 6 month cardiac readmissions. The effect size of CSA exceeded that of all known predictors of heart failure readmissions.
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影响因子：
37.8
作者：
Dai Yumino;Redolfi, Stefania;Bradley, T. Douglas
通讯作者：
Bradley, T. Douglas
影响因子：
5.6
作者：
Leung, RST;Diep, TM;Bradley, TD
通讯作者：
Bradley, TD
DOI：
10.1016/s0034-5687(99)00114-0
发表时间：
2000-02-01
期刊：
RESPIRATION PHYSIOLOGY
影响因子：
--
作者：
Fletcher, EC
通讯作者：
Fletcher, EC
影响因子：
37.8
作者：
Javaheri, S;Parker, TJ;Roselle, GA
通讯作者：
Roselle, GA
影响因子：
37.8
作者：
Javaheri, S
通讯作者：
Javaheri, S