Manipulation of Hyperbaric Lidocaine Using a Weak Magnetic Field: A Pilot Study

Manipulation of Hyperbaric Lidocaine Using a Weak Magnetic Field: A Pilot Study
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使用弱磁场操纵高压利多卡因:初步研究

DOI:
10.1213/ane.0b013e31824cb835
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发表时间:
2012
影响因子:
5.7
通讯作者:
M. Tiouririne
M. Tiouririne
中科院分区:
医学2区
文献类型:
--
作者:
R. Thiele;Douglas A Colquhoun;G. Gillies;M. Tiouririne

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高位脊髓阻滞是脊髓麻醉的潜在致命并发症,发生率为0.6/1000。目前的预防策略包括减少局部麻醉药物的剂量和改变患者的体位,使高压麻醉药物在神经轴中的位置可以通过重力来操纵。将铁磁流体并入局部麻醉剂溶液中,结合体外脊柱模型中的外部磁场的应用,允许控制铁磁流体、染料和局部麻醉剂的溶液对抗重力的位置,这表明麻醉提供者可以通过其防止高位脊柱阻滞的另外的机制。
High spinal block is a potentially fatal complication of spinal anesthesia, with an incidence of 0.6 per 1000. Current prevention strategies include decreasing the dose of local anesthetic drug and altering patient positioning such that the location of hyperbaric anesthetic drugs in the neuraxis can be manipulated by gravity. Incorporation of a ferrofluid into a local anesthetic solution, combined with application of an external magnetic field in an in vitro spine model, allowed control of position of a solution of ferrofluid, dye, and local anesthetic against gravity, suggesting an additional mechanism by which anesthesia providers may prevent high spinal block.
磁立体定向:一种提供立体定向热疗的技术。
DOI: --
发表时间: 1990
期刊: Neurosurgery
影响因子: 4.8
作者:
Grady,MS;Howard3rd,MA;Broaddus,WC;Molloy,JA;Ritter,RC;Quate,EG;Gillies,GT
通讯作者: Gillies,GT