SAMPLE SELECTION AND THE NATURAL-HISTORY OF DISEASE - STUDIES OF FEBRILE SEIZURES
SAMPLE SELECTION AND THE NATURAL-HISTORY OF DISEASE - STUDIES OF FEBRILE SEIZURES
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DOI：
10.1001/jama.243.13.1337
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发表时间：
1980-01-01
影响因子：
120.7
通讯作者：
NELSON, KB
中科院分区：
文献类型：
--
作者：
ELLENBERG, JH;NELSON, KB
已发表的报告对从医院诊所或转诊单位确定的一种常见的儿童疾病--发热性癫痫--的不良后遗症的发生率进行了比较，并与基于人群的研究报告的频率进行了比较。对确定的人群进行的研究，其中试图识别和跟踪所有受影响的人，而不考虑为这种情况寻求的医疗护理，并表明不良后遗症的比率相对较低。基于临床的热性惊厥研究报告了不同的结果，包括高频率的不良结果。一种可能的解释是，以临床为基础的研究中的患者可能不代表普通人群中患有这种疾病的人。
Published reports were compared on the frequency of unfavorable sequelae in a common disorder of childhood, febrile seizures, as ascertained from hospital clinics or referral units, with the frequency as reported from population-based studies. Studies on defined populations, in which the attempt was made to recognize and follow up all affected persons regardless of medical care sought for the condition, and indicate relatively low rates of unfavorable sequelae. Clinic-based studies of febrile seizures reported disparate results, including high frequencies of adverse outcomes. A possible explanation is that patients in clinic-based studies may not be representative of persons with the disorder in the general population.