Efficient synthesis of quinazoline-2,4(1H,3H)-diones from CO2 and 2-aminobenzonitriles in water without any catalyst

Efficient synthesis of quinazoline-2,4(1H,3H)-diones from CO2 and 2-aminobenzonitriles in water without any catalyst
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无需任何催化剂,CO2 和 2-氨基苯甲腈在水中高效合成喹唑啉-2,4(1H,3H)-二酮

DOI:
10.1039/c3gc00091e
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发表时间:
2013-01-01
期刊:
影响因子:
9.8
通讯作者:
Hou, Minqiang
Hou, Minqiang
中科院分区:
化学1区
文献类型:
--
作者:
Ma, Jun;Han, Buxing;Hou, Minqiang

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We discovered that the synthesis of quinazoline-2,4(1H,3H)-diones from CO2 and 2-aminobenzonitriles could proceed efficiently in water without any catalyst and excellent yields were obtained, while the reaction did not occur in organic solvents. This green and simple route to synthesize quinazoline-2,4(1H,3H)-diones has great potential for application.