Effectiveness of peer support on care engagement and preventive care intervention utilization among pre-antiretroviral therapy, HIV-infected adults in Rakai, Uganda: a randomized trial.
Effectiveness of peer support on care engagement and preventive care intervention utilization among pre-antiretroviral therapy, HIV-infected adults in Rakai, Uganda: a randomized trial.
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DOI：
10.1007/s10461-015-1159-y
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发表时间：
2015-10
影响因子：
4.4
通讯作者：
Reynolds SJ
中科院分区：
文献类型：
--
作者：
Chang LW;Nakigozi G;Billioux VG;Gray RH;Serwadda D;Quinn TC;Wawer MJ;Bollinger RC;Reynolds SJ
将442名接受抗逆转录病毒治疗前的艾滋病毒感染成年人随机分配到同伴支持组，包括结构化家访，以促进诊所就诊和预防性护理干预措施的使用或护理标准。在基线时，62%的人报告以前去过艾滋病毒诊所，45%的人报告服用复方新诺明预防剂，31%的人是“初治”（以前没有去过诊所，也没有服用复方新诺明）。一年后，干预参与者更有可能报告接受护理（92% vs 84%; PRR 1.09，p=0.039），服用复方新诺明（89% vs 81%; PRR 1.10，p=0.047）和安全水容器依从性（23% vs 14%; PRR 1.64，p=0.024）。仅在未接受过护理的参与者（n=139）中观察到这种效果，83%的干预组与53%的对照组报告接受了艾滋病毒护理（PRR 1.47，p=0.006），78%与58%的复方新诺明（PRR 1.35，p=0.04），20%与4%的安全水容器依从性（PRR 5.78，p=0.017）。同伴的支持可能是一种有效的干预措施，以促进在这个重要的人口的ART前护理的依从性。
442 pre-ART, HIV-infected adults were randomized to peer support consisting of structured home visits to promote clinic attendance and preventive care intervention use or standard of care. At baseline, 62% reported previously visiting an HIV clinic, 45% reported taking cotrimoxazole prophylaxis, and 31% were “care-naïve” (no previous clinic visit and not on cotrimoxazole). After one year, intervention participants were more likely to report being in care (92% vs 84%; PRR 1.09, p=0.039), on cotrimoxazole (89% vs 81%; PRR 1.10, p=0.047), and safe water vessel adherence (23% vs 14%; PRR 1.64, p=0.024). The effect was observed only among care-naïve participants (n=139) with 83% intervention vs 53% controls reporting being in HIV care (PRR 1.47, p=0.006), 78% vs 58% on cotrimoxazole (PRR 1.35, p=0.04), and 20% vs 4% safe water vessel adherence (PRR 5.78, p=0.017). Peer support may be an effective intervention to facilitate pre-ART care compliance in this important population.