Techniques and Outcomes of MRI-TRUS Fusion Prostate Biopsy.
Techniques and Outcomes of MRI-TRUS Fusion Prostate Biopsy.
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DOI：
10.1007/s11934-021-01037-x
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发表时间：
2021-03-22
影响因子：
2.6
通讯作者：
Abreu AL
中科院分区：
文献类型：
--
作者：
Kaneko M;Sugano D;Lebastchi AH;Duddalwar V;Nabhani J;Haiman C;Gill IS;Cacciamani GE;Abreu AL
本研究的目的是回顾最近的研究结果，评价MRI经直肠超声融合活检（FBx）技术的实用性，并讨论未来的发展方向。与超声引导系统性前列腺活检（SBx）相比，FBx检测到临床显著性前列腺癌（csPCa）的发生率显著更高，特别是在重复活检设置中。FBx还被证明可以显著降低临床上无意义的前列腺癌的检出率。此外，专用的前列腺MRI可以帮助更准确地预测格里森评分，并提供有关索引癌症位置，前列腺体积和临床分期的进一步信息。准确评估特定病变的能力对于病灶治疗和主动监测、治疗选择、计划和充分随访至关重要。多项高质量研究已证明，与SBx相比，FBx在诊断csPCa方面的性能有所改善。FBx与放射组学、前列腺特异性膜抗原正电子发射断层扫描（PSMA PET）和高分辨率微超声等新技术的结合可能有可能进一步提高这一性能。
The goal of this study is to review recent findings and evaluate the utility of MRI transrectal ultrasound fusion biopsy (FBx) techniques and discuss future directions. FBx detects significantly higher rates of clinically significant prostate cancer (csPCa) than ultrasound-guided systematic prostate biopsy (SBx), particularly in repeat biopsy settings. FBx has also been shown to detect significantly lower rates of clinically insignificant prostate cancer. In addition, a dedicated prostate MRI can assist in more accurately predicting the Gleason score and provide further information regarding the index cancer location, prostate volume, and clinical stage. The ability to accurately evaluate specific lesions is vital to both focal therapy and active surveillance, for treatment selection, planning, and adequate follow-up. FBx has been demonstrated in multiple high-quality studies to have improved performance in diagnosis of csPCa compared to SBx. The combination of FBx with novel technologies including radiomics, prostate-specific membrane antigen positron emission tomography (PSMA PET), and high-resolution micro-ultrasound may have the potential to further enhance this performance.
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