Iridium-catalyzed borylation of arenes and heteroarenes via C-H activation
Iridium-catalyzed borylation of arenes and heteroarenes via C-H activation
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DOI：
10.1351/pac200678071369
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发表时间：
2006-07-01
影响因子：
1.8
通讯作者：
Miyaura, Norio
中科院分区：
文献类型：
--
作者：
Ishiyama, Tatsuo;Miyaura, Norio
研究了过渡金属配合物催化芳香化合物的C-H硼化反应，作为一种经济的合成芳香硼衍生物的方法。由Ir（I）前体和2，2 '-联吡啶配体生成的铱配合物有效地催化芳烃和杂芳烃与双（频哪醇合）二硼或频哪醇硼烷的反应，以产生各种芳基-和杂芳基硼化合物。催化循环涉及三（硼基）铱（III）物质的形成及其氧化加成到芳香族C-H键。
Direct C-H borylation of aromatic compounds catalyzed by a transition-metal complex was studied as an economical protocol for the synthesis of aromatic boron derivatives. Iridium complexes generated from Ir(l) precursors and 2,2'-bipyridine ligands efficiently catalyzed the reactions of arenes and heteroarenes with bis(pinacolato)diboron or pinacolborane to produce a variety of aryl- and heteroarylboron compounds. The catalytic cycle involves the formation of a tris(boryl)iridium(III) species and its oxidative addition to an aromatic C-H bond.