Outer retina ischemic infarction--a newly recognized complication of cataract extraction and closed vitrectomy. Part 2. An animal model.
Outer retina ischemic infarction--a newly recognized complication of cataract extraction and closed vitrectomy. Part 2. An animal model.
复制标题
外视网膜缺血性梗塞——一种新认识的白内障摘除术和闭合性玻璃体切除术的并发症。
DOI：
10.1016/s0161-6420(82)34614-x
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发表时间：
1982
期刊：
影响因子：
13.7
通讯作者：
Anderson,DR
中科院分区：
文献类型：
--
作者：
Parrish,R;Gass,JD;Anderson,DR
在40只猫头鹰猴眼中，人工升高眼内压至高于收缩压。在高压90分钟或更长时间的10只眼睛中有9只眼睛产生了后极部弥漫性视网膜变白和随后的视网膜色素上皮破裂，但也有少数眼睛高压持续时间较短。眼底血管造影及组织学检查显示光感受器及视网膜色素上皮细胞受损，但视网膜内层未受损。该动物模型复制了由于外部视网膜梗塞引起的急性视力丧失，外部视网膜梗塞有时发生在闭合玻璃体切除术后或在准备手术的连续外部眼压迫后。
Intraocular pressure was artificially elevated above systolic blood pressure in 40 owl monkey eyes. Diffuse retinal whitening of the posterior pole and subsequent retinal pigment epithelial disruption were produced in nine of ten eyes with high pressure for 90 minutes or longer, but also in a few eyes with high pressure for a shorter duration. Fluorescein angiography and histologic examination demonstrated damage of the photoreceptors and retinal pigment epithelium with sparing of the inner retinal layers. This animal model duplicates the acute visual loss due to outer retinal infarction that sometimes occurs after closed vitrectomy or after continuous external ocular compression in preparation for surgery.