Nonlinear blood pressure effects on cognition in old age: separating between-person and within-person associations.
Nonlinear blood pressure effects on cognition in old age: separating between-person and within-person associations.
复制标题
非线性血压对老年认知的影响:分离人与人之间的关联。
DOI:
10.1037/a0025631
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发表时间:
2012
影响因子:
3.7
通讯作者:
Johansson,Boo
中科院分区:
文献类型:
--
作者:
Thorvaldsson,Valgeir;Skoog,Ingmar;Hofer,ScottM;Borjesson-Hanson,Anne;Ostling,Svante;Sacuiu,Simona;Johansson,Boo
Midlife hypertension is associated with increased risk of cognitive impairment in later life. The association between blood pressure (BP) in older ages and cognition is less clear. In this study we provide estimates of between-person and within-person associations of BP and cognition in a population-based sample (N= 382) followed from age 70 across 12 occasions over 30 years. Between-person associations refer to how individual differences in BP relates to individual differences in cognition. Within-person associations refer to how individual and time specific changes in BP relate to variation in cognition. Hierarchical linear models were fitted to data from three cognitive measurements (verbal ability, spatial ability, and perceptual speed) while accounting for demographic and health-related covariates. We found consistent nonlinear between-person associations between diastolic BP (DBP) and cognition, such that both low (< 75 mmHg) and high (> 95 mmHg) pressure were associated with poorer cognition. Within-person decreases in systolic BP (SBP) and DBP were associated with decreases in perceptual speed. Notably, between-person and within-person estimates did not reveal similar associations, suggesting the need to separate the two effects in the analysis of associations between BP and cognition in old age.(PsycInfo Database Record (c) 2020 APA, all rights reserved)
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影响因子:
--
作者:
RINDER, L;ROUPE, S;SVANBORG, A
通讯作者:
SVANBORG, A
DOI:
10.1001/jama.1995.03530230032026
发表时间:
1995-12
期刊:
JAMA
影响因子:
--
作者:
L. Launer;K. Masaki;H. Petrovitch;D. Foley;R. Havlik
通讯作者:
L. Launer;K. Masaki;H. Petrovitch;D. Foley;R. Havlik
影响因子:
2.4
作者:
Molander, Lena;Gustafson, Yngve;Lovheim, Hugo
通讯作者:
Lovheim, Hugo
DOI:
--
发表时间:
1980
期刊:
Acta Psychiatrica Scandinavica Supplementum
影响因子:
--
作者:
S. Berg
通讯作者:
S. Berg
影响因子:
5
作者:
Zhenchao Guo;Laura Fratiglioni;Bengt Winblad;Matti Viitanen
通讯作者:
Matti Viitanen