Isolation and characterization of a stage-specific transforming gene, Tlym-I, from T-cell lymphomas.
Isolation and characterization of a stage-specific transforming gene, Tlym-I, from T-cell lymphomas.
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T 细胞淋巴瘤阶段特异性转化基因 Tlym-I 的分离和表征。
DOI：
10.1073/pnas.81.7.2227
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发表时间：
1984
影响因子：
11.1
通讯作者：
Cooper,GM
中科院分区：
文献类型：
--
作者：
Lane,MA;Sainten,A;Doherty,KM;Cooper,GM
通过分子克隆技术，分离到一个由小鼠T细胞淋巴瘤DNA转染检测到的细胞转化基因。该基因（命名为TAP-I）与正常小鼠和人DNA中存在的一个小的保守序列家族同源，但与任何先前描述的病毒或细胞转化基因无关。
A cellular transforming gene detected by transfection of mouse T-cell lymphoma DNA has been isolated by molecular cloning. This gene (designated Tlym-I) is homologous to a small conserved family of sequences present in normal mouse and human DNAs but is not related to any of the previously described viral or cellular transforming genes.