A novel cardiac output response to stress test developed to improve diagnosis and monitoring of heart failure in primary care.
A novel cardiac output response to stress test developed to improve diagnosis and monitoring of heart failure in primary care.
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DOI：
10.1002/ehf2.12302
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发表时间：
2018-08
影响因子：
3.8
通讯作者：
Jakovljevic DG
中科院分区：
文献类型：
--
作者：
Charman SJ;Okwose NC;Stefanetti RJ;Bailey K;Skinner J;Ristic A;Seferovic PM;Scott M;Turley S;Fuat A;Mant J;Hobbs RFD;MacGowan GA;Jakovljevic DG
Primary care physicians lack access to an objective cardiac function test. This study for the first time describes a novel cardiac output response to stress (CORS) test developed to improve diagnosis and monitoring of heart failure in primary care and investigates its reproducibility. Prospective observational study recruited 32 consecutive primary care patients (age, 63 ± 9 years; female, n = 18). Cardiac output was measured continuously using the bioreactance method in supine and standing positions and during two 3 min stages of a step‐exercise protocol (10 and 15 steps per minute) using a 15 cm height bench. The CORS test was performed on two occasions, i.e. Test 1 and Test 2. There was no significant difference between repeated measures of cardiac output and stroke volume at supine standing and Stage 1 and Stage 2 step exercises (all P > 0.3). There was a significant positive relationship between Test 1 and Test 2 cardiac outputs (r = 0.92, P = 0.01 with coefficient of variation of 7.1%). The mean difference in cardiac output (with upper and lower limits of agreement) between Test 1 and Test 2 was 0.1 (−1.9 to 2.1) L/min, combining supine, standing, and step‐exercise data. The CORS, as a novel test for objective evaluation of cardiac function, demonstrates acceptable reproducibility and can potentially be implemented in primary care.
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射血分数保留的心力衰竭运动不耐受的机制：异常外周氧提取的作用。
DOI：
10.1161/circheartfailure.114.001825
发表时间：
2015-03
期刊：
Circulation. Heart failure
影响因子：
--
作者：
Dhakal BP;Malhotra R;Murphy RM;Pappagianopoulos PP;Baggish AL;Weiner RB;Houstis NE;Eisman AS;Hough SS;Lewis GD
通讯作者：
Lewis GD
DOI：
10.1136/bmj.h910
发表时间：
2015-03-04
期刊：
BMJ (Clinical research ed.)
影响因子：
--
作者：
Roberts E;Ludman AJ;Dworzynski K;Al-Mohammad A;Cowie MR;McMurray JJ;Mant J;NICE Guideline Development Group for Acute Heart Failure
通讯作者：
NICE Guideline Development Group for Acute Heart Failure
影响因子：
37.8
作者：
Kelder, Johannes C.;Cramer, Maarten J.;Hoes, Arno W.
通讯作者：
Hoes, Arno W.
影响因子：
9.8
作者：
Jones, T. W.;Houghton, D.;Jakovljevic, D. G.
通讯作者：
Jakovljevic, D. G.
影响因子：
38.9
作者：
Squara, Pierre;Denjean, Dominique;Dubois, Claude
通讯作者：
Dubois, Claude