Paper spray and Kendrick mass defect analysis of block and random ethylene oxide/propylene oxide copolymers
Paper spray and Kendrick mass defect analysis of block and random ethylene oxide/propylene oxide copolymers
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嵌段和无规环氧乙烷/环氧丙烷共聚物的纸喷雾和 Kendrick 质量缺陷分析
DOI：
10.1016/j.aca.2017.08.005
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发表时间：
2017
影响因子：
6.2
通讯作者：
Fouquet Thierry
中科院分区：
文献类型：
--
作者：
Cody Robert B.;Fouquet Thierry
纸喷雾电离耦合高分辨率飞行时间质谱仪应用于分析13个嵌段和2个随机环氧乙烷/环氧丙烷（EO/PO）共聚物以及聚（环氧乙烷）和聚（环氧丙烷）均聚物的标准样品。纸喷雾质谱可以快速获得，不像电喷雾电离，不受污染和样品携带。为了进行比较，还在MALDI/TOF系统上测量了聚醚样品，该系统具有较高的质量分辨能力。MALDI/高分辨率飞行时间质谱法显示出聚合物分布的单电荷离子特征，而纸喷雾质谱法显示出一到六个电荷的电荷状态。在纸喷雾质谱中的多电荷离子的肯德里克质量亏损图表现出同位素分裂的肯德里克质量亏损，便于可视化的电荷数在每个系列。KMD曲线的斜率可用于估计共聚物中环氧乙烷的百分比。在源分裂允许之间的区别嵌段和无规共聚物。
Paper spray ionization coupled with a high-resolution time-of-flight mass spectrometer was applied to the analysis of 13 block and 2 random ethylene oxide/propylene oxide (EO/PO) copolymers as well as to standard samples of poly(ethylene oxide) and poly(propylene oxide) homopolymers. Paper spray mass spectra could be obtained rapidly and, unlike electrospray ionization, were not subject to contamination and sample carryover. For comparison, polyether samples were also measured on a MALDI/TOF system with ultrahigh mass resolving power. MALDI/high-resolution time-of-flight mass spectrometry exhibited single-charge ions characteristic of the polymer distributions whereas the paper spray mass spectra exhibited charge states ranging from one to six charges. Kendrick mass defect plots of the multiple-charge ions in the paper spray mass spectra exhibit isotopic splitting of the Kendrick mass defects, facilitating visualization of the number of charges in each series. The slope of the KMD plots can be used to estimate the percentage of ethylene oxide in the copolymers. In-source fragmentation permitted the distinction between block and random copolymers.