The Influence of Time from Injury to Surgery on Motor Recovery and Length of Hospital Stay in Acute Traumatic Spinal Cord Injury: An Observational Canadian Cohort Study
The Influence of Time from Injury to Surgery on Motor Recovery and Length of Hospital Stay in Acute Traumatic Spinal Cord Injury: An Observational Canadian Cohort Study
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DOI：
10.1089/neu.2014.3632
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发表时间：
2015-05-01
影响因子：
4.2
通讯作者：
Fehlings, Michael G.
中科院分区：
文献类型：
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作者：
Dvorak, Marcel F.;Noonan, Vanessa K.;Fehlings, Michael G.
为了确定从损伤到手术的时间对创伤性脊髓损伤(TSCI)患者观察队列中神经恢复和住院时间(LOS)的影响，我们分析了Rick Hansen脊髓损伤登记处参与者的基线和随访运动评分，以具体评估早期(离损伤不到24小时)手术对运动恢复和LOS的影响。对1,410例急性脊髓损伤患者进行了手术治疗，分析了手术时机(伤后24、48或72小时)对运动恢复和LOS的影响。根据数据分布的不同，我们使用了不同类型的广义线性模型，包括多元线性回归、伽玛回归和负二项回归。从C2到L2的不完全AIS B、C和D损伤患者的运动恢复改善了6.3个运动点(SE=2.8 p
To determine the influence of time from injury to surgery on neurological recovery and length of stay (LOS) in an observational cohort of individuals with traumatic spinal cord injury (tSCI), we analyzed the baseline and follow-up motor scores of participants in the Rick Hansen Spinal Cord Injury Registry to specifically assess the effect of an early (less than 24 h from injury) surgical procedure on motor recovery and on LOS. One thousand four hundred and ten patients who sustained acute tSCIs with baseline American Spinal Injury Association Impairment Scale (AIS) grades A, B, C, or D and were treated surgically were analyzed to determine the effect of the timing of surgery (24, 48, or 72 h from injury) on motor recovery and LOS. Depending on the distribution of data, we used different types of generalized linear models, including multiple linear regression, gamma regression, and negative binomial regression. Persons with incomplete AIS B, C, and D injuries from C2 to L2 demonstrated motor recovery improvement of an additional 6.3 motor points (SE=2.8 p