In vitro activities of 10 combinations of antifungal agents against the multiresistant pathogen Scopulatiopsis brevicaulis
In vitro activities of 10 combinations of antifungal agents against the multiresistant pathogen Scopulatiopsis brevicaulis
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DOI：
10.1128/aac.00162-06
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发表时间：
2006-06-01
影响因子：
4.9
通讯作者：
Rodriguez-Tudela, JL
中科院分区：
文献类型：
--
作者：
Cuenca-Estrella, M;Gomez-Lopez, A;Rodriguez-Tudela, JL
通过棋盘技术测试了 10 种抗真菌药物组合对 25 种短柄帚霉临床分离株的活性。所有组合均检测到平均无差异效应。一些分离株和组合观察到协同作用，特别是泊沙康唑-特比萘芬（68%的菌株）、两性霉素 B-卡泊芬净（60%）和泊沙康唑-卡泊芬净（48%）。
The activities of 10 combinations of antifungal agents against 25 clinical isolates of Scopulariopsis brevicaulis were tested by the checkerboard technique. An average indifferent effect was detected for all combinations. Synergy was observed for some isolates and combinations, particularly with posaconazole-terbinafine (68% of strains), amphotericin B-caspofungin (60%), and posaconazole-caspofungin (48%).