Amygdala damage impairs eye contact during conversations with real people
Amygdala damage impairs eye contact during conversations with real people
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DOI：
10.1523/jneurosci.3789-06.2007
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发表时间：
2007-04-11
影响因子：
5.3
通讯作者：
Adolphs, Ralph
中科院分区：
文献类型：
--
作者：
Spezio, Michael L.;Huang, Po-Yin Samuel;Adolphs, Ralph
人类杏仁核在真实社会互动中的作用基本上仍然未知，尽管对非人类灵长类动物的研究以及使用人类照片和视频的研究表明它对情感处理至关重要，并表明它对社会认知的重要性。我们在这里表明，完整的杏仁核损伤会导致与真人交谈时直接目光接触的严重减少，以及对嘴部注视的异常增加。这些来自真实社会互动的新发现与杏仁核在自闭症中的假设作用一致，这里采取的方法为量化人类社会行为开辟了新方向。
The role of the human amygdala in real social interactions remains essentially unknown, although studies in nonhuman primates and studies using photographs and video in humans have shown it to be critical for emotional processing and suggest its importance for social cognition. We show here that complete amygdala lesions result in a severe reduction in direct eye contact during conversations with real people, together with an abnormal increase in gaze to the mouth. These novel findings from real social interactions are consistent with an hypothesized role for the amygdala in autism and the approach taken here opens up new directions for quantifying social behavior in humans.