Reductive Heck Reaction: An Emerging Alternative in Natural Product Synthesis
Reductive Heck Reaction: An Emerging Alternative in Natural Product Synthesis
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DOI：
10.1002/slct.201804029
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发表时间：
2019-04-29
期刊：
影响因子：
2.1
通讯作者：
Ghosh, Tapas
中科院分区：
文献类型：
--
作者：
Ghosh, Tapas
金属催化的交叉偶联反应是合成多种杂环化合物的有效方法，广泛存在于天然产物中。其中，还原Heck反应被巧妙地应用于各种天然产物的获取。本文综述了还原Heck反应在天然产物合成中应用的最新文献。在任何认为有必要的地方，也都包括了对根本机制理论基础的讨论。
Metal-catalyzed cross coupling reactions are efficient synthetic methods and developing continuously for the synthesis of diverse range of heterocycles, found in wide range of natural products. Among others, reductive Heck reaction has elegantly been employed to access various natural products. This review article covers the updated summary of relevant literature on the application of reductive Heck reaction for the synthesis of natural products. Discussion on the underlying mechanistic rationale has also been included wherever felt necessary.