Development of Extracellular Matrices Mimicking Stepwise Adipogenesis of Mesenchymal Stem Cells

Development of Extracellular Matrices Mimicking Stepwise Adipogenesis of Mesenchymal Stem Cells
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DOI:
10.1002/adma.201000038
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发表时间:
2010-07-27
期刊:
影响因子:
29.4
通讯作者:
Chen, Guoping
Chen, Guoping
中科院分区:
材料科学1区
文献类型:
--
作者:
Hoshiba, Takashi;Kawazoe, Naoki;Chen, Guoping

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一种新型的细胞外基质,即逐步脂肪生成模拟基质,是由控制在脂肪生成不同阶段的培养间充质干细胞开发的。干细胞来源的基质以及脂肪形成早期和晚期控制的细胞对干细胞分化表现出不同的影响。
A novel type of extracellular matrices, stepwise adipogenesis-mimicking matrices, was developed from cultured mesenchymal stem cells controlled at different stages of adipogenesis. The matrices derived from stem cells, and the cells controlled at early and late stages of adipogenesis showed different effects on stem cell differentiation.