EFFECT OF PHASIC RESPIRATION ON LEFT-VENTRICULAR DIMENSION AND PERFORMANCE IN A NORMAL POPULATION - ECHOCARDIOGRAPHIC STUDY
EFFECT OF PHASIC RESPIRATION ON LEFT-VENTRICULAR DIMENSION AND PERFORMANCE IN A NORMAL POPULATION - ECHOCARDIOGRAPHIC STUDY
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DOI：
10.1161/01.cir.57.1.122
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发表时间：
1978-01-01
期刊：
影响因子：
37.8
通讯作者：
WAUGH, RA
中科院分区：
文献类型：
--
作者：
BRENNER, JI;WAUGH, RA
本文对30例5 ~ 47岁正常人左心室（LV）进行超声心动图检查，分析相呼吸对左心室尺寸及衍生左心室功能的影响。测量呼气峰和吸气峰左室舒张和收缩尺寸，并使用标准公式推断出容积估计值。尽管个体测量值存在很大差异，特别是在收缩尺寸上，但吸气舒张平均峰值尺寸、衍生舒张容积和卒中容积均显著降低（P < 0.001）；射血分数下降幅度较小（P < 0.02）；平均收缩末尺寸和收缩末容积变化无统计学意义。虽然这些观察到的变化可能反映了真实的生理变化，但不能排除人为成分。无论其生理学意义如何，这些数据表明，在正常和可能的病理性心血管疾病的左室功能的相关超声心动图研究中，相位呼吸的影响是一个需要考虑的因素。
Echocardiographic examination of the left ventricle (LV) in 30 normal subjects, 5-47 yr old was performed to analyze the effects of phasic respiration on LV dimensions and derived LV functions. Peak expiratory and peak inspiratory LV diastolic and systolic dimensions were measured and extrapolated to volume estimates using a standard formula. Although there was wide variation in the individual measurements, and particularly in systolic dimension, the mean peak inspiratory diastolic dimension, derived diastolic volume and stroke volune decreased significantly (P < 0.001); a smaller decrease in ejection fraction was seen (P < 0.02); the changes in mean end-systolic dimension and end-systolic volume were not significant. While these observed changes may reflect a true physiologic variation, an artifactual component cannot be excluded. Regardless of their physiologic significance, these data show that the effect of phasic respiration is a factor to be considered in correlative echocardiographic studies of LV function in normal and, possibly, pathologic cardiovascular conditions.