A Helicobacter pylori screening and treatment program to eliminate gastric cancer among junior high school students in Saga Prefecture: a preliminary report

A Helicobacter pylori screening and treatment program to eliminate gastric cancer among junior high school students in Saga Prefecture: a preliminary report
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DOI:
10.1007/s00535-019-01559-9
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发表时间:
2019-08-01
影响因子:
6.3
通讯作者:
Fujimoto, Kazuma
Fujimoto, Kazuma
中科院分区:
医学1区
文献类型:
--
作者:
Kakiuchi, Toshihiko;Matsuo, Muneaki;Fujimoto, Kazuma

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背景介绍佐贺县实施幽门螺杆菌筛查和根除计划预防胃癌后前3年的策略和初步结果。2016年,佐贺县利用地方政府赠款,开始对初中三年级学生进行幽门螺杆菌检测。筛查采用尿抗H。pylori抗体检测,其次是H.对抗体呈阳性的学生进行幽门螺杆菌粪便抗原测试。两项检测均呈阳性的患者接受了H.通过基于钾竞争性酸阻滞剂的三联疗法根除幽门螺杆菌。结果2016年至2018年,参与率为83.1%,H. pylori感染率为3.1%(660/21,042)。与2016年(78.5%)相比,2017年(85.4%)和2018年(85.9%)的参与率更高(P
BackgroundTo present the strategies and preliminary findings of the first 3years after implementing a Helicobacter pylori screening and eradication program to prevent gastric cancer in Saga Prefecture.MethodsA screening and treatment program to eradicate H. pylori from third-grade junior high students was started in Saga Prefecture in 2016, using local governmental grants. Screening was with urinary anti-H. pylori antibody tests, followed by H. pylori stool antigen tests for students who were antibody positive. Those positive on both tests underwent H. pylori eradication by triple therapy based on a potassium-competitive acid blocker.ResultsFrom 2016 to 2018, the participation rate was 83.1% and the H. pylori infection rate was 3.1% (660/21,042). The participation rates were higher in 2017 (85.4%) and 2018 (85.9%) compared with 2016 (78.5%) (P