The EMBL Nucleotide Sequence Database
The EMBL Nucleotide Sequence Database
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DOI：
10.1093/nar/27.1.18
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发表时间：
1999-01-01
影响因子：
14.9
通讯作者：
Sterk, P
中科院分区：
文献类型：
--
作者：
Stoesser, G;Tuli, MA;Sterk, P
EMBL核苷酸序列数据库（http：//www.ebi.ac.uk/embl.html）构成欧洲的主要核苷酸序列资源。DNA和RNA序列的主要来源是个人研究人员、基因组测序项目和专利申请的直接提交。虽然自动程序允许从大规模基因组测序中心和欧洲专利局（EPO）的序列数据的整合，个人提交者的首选提交工具是Webin（WWW）。在所有阶段，EBI生物学家都在与测序小组进行沟通，以监测EBI的工作。与DDBJ和GenBank合作，在欧洲生物信息学研究所（EBI）制作、维护和分发数据库。数据库每季度发布一次，并以光盘形式分发，网络服务使人们能够通过互联网和万维网接口查阅最新的数据收集。EBl的序列检索系统（SRS）是分子生物学数据库的网络浏览器，集成和链接主要的核苷酸和蛋白质数据库，以及许多专业数据库。对于序列相似性搜索，外部用户可以使用各种工具（例如，Blitz、Pasta、Blast等）将其自己的序列与EMBL核苷酸序列数据库和SWISS-PROT中最新可用的数据进行比较。
The EMBL Nucleotide Sequence Database (http://www.ebi.ac.uk/embl.html) constitutes Europe's primary nucleotide sequence resource. Main sources for DNA and RNA sequences are direct submissions from individual researchers, genome sequencing projects and patent applications. While automatic procedures allow incorporation of sequence data from large-scale genome sequencing centres and from the European Patent Office (EPO), the preferred submission tool for individual submitters is Webin (WWW). Through all stages, dataflow is monitored by EBI biologists communicating with the sequencing groups. In collaboration with DDBJ and GenBank the database is produced, maintained and distributed at the European Bioinformatics Institute (EBI). Database releases are produced quarterly and are distributed on CD-ROM, Network services allow access to the most up-to-date data collection via Internet and World Wide Web interface. EBl's Sequence Retrieval System (SRS) is a Network Browser for Databanks in Molecular Biology, integrating and linking the main nucleotide and protein databases, plus many specialised databases. For sequence similarity searching a variety of toots (e.g, Blitz, Pasta, Blast etc) are available for external users to compare their own sequences against the most currently available data in the EMBL Nucleotide Sequence Database and SWISS-PROT.