Cannabinoid Poisoning-Related Emergency Department Visits and Inpatient Hospitalizations in Kentucky, 2017 to 2019.
Cannabinoid Poisoning-Related Emergency Department Visits and Inpatient Hospitalizations in Kentucky, 2017 to 2019.
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2017 年至 2019 年肯塔基州与大麻素中毒相关的急诊就诊和住院治疗。
DOI：
10.1080/10826084.2022.2148478
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发表时间：
2023
影响因子：
2
通讯作者：
Slavova,Svetla
中科院分区：
文献类型：
--
作者：
Britch,StevieC;Walsh,SharonL;Vickers-Smith,Rachel;Babalonis,Shanna;Slavova,Svetla
背景和目标：大麻是最常用的联邦非法物质。由于广泛的药用用途和州级合法化，公众对大麻的看法已经转向大麻是安全的假设。然而，大麻素可能会引起不良的医疗并发症，可能导致人们寻求治疗。本研究描述了与大麻素中毒相关的医疗事件、涉及大麻素和其他精神活性物质的中毒以及与大麻素中毒相关的心脏并发症。方法：使用出院日期为 2017 年 1 月 1 日至 2019 年 12 月 31 日的急症护理机构的急诊科就诊和住院患者的行政账单数据来描述肯塔基州大麻素中毒事件的特征，由 ICD-10-CM 诊断代码识别T40.7X.结果：有 1,490 起大麻素中毒事件；患者主要是 15 至 44 岁的非西班牙裔白人男性，他们享有医疗补助并居住在大都市区。其中，31.21% 涉及第二种精神活性物质（主要是兴奋剂和/或阿片类药物）中毒，17.72% 出现心脏并发症。大麻素多种药物中毒与住院治疗（χ2=199.18，p< 0.001）和心脏并发症（χ2=4.58，p< 0.001）相关。讨论和结论：这些结果与其他州级数据一致。与单纯大麻中毒相比，被诊断为大麻多种药物中毒的患者入院和心脏并发症的几率更高，住院时间也更长。科学意义：必须更广泛地认识到大麻素使用的健康风险，同时需要及时共享准确的数据来指导大麻获取政策。未来对大麻素中毒的研究应考虑其他精神活性药物的参与。
Background and objectives: Cannabis is the most used federally illicit substance. Due to widespread medicinal use and state-level legalization, public perceptions of cannabis have shifted toward the assumption that cannabis is safe. However, cannabinoids can cause adverse medical complications that may lead people to seek treatment. This study characterized cannabinoid poisoning-related medical encounters, poisoning involving cannabinoids and other psychoactive substances, and cannabinoid poisoning-related cardiac complications.Methods: Administrative billing data for emergency department visits and inpatient hospitalizations in acute care facilities with a discharge date from January 1, 2017 to December 31, 2019 were used to characterize cannabinoid poisoning events in Kentucky, identified by ICD-10-CM diagnosis code T40.7X.Results:There were 1,490 encounters of cannabinoid poisoning; patients were primarily non-Hispanic White males, ages 15–44, who had Medicaid and lived in a metropolitan area. Of those, 31.21% involved poisoning with a second psychoactive substance, primarily stimulants and/or opioids, and 17.72% experienced a cardiac complication. Cannabinoid-polydrug poisoning was associated with inpatient treatment (χ2=199.18,p< 0.001) and cardiac complications (χ2=4.58,p< 0.001).Discussion and Conclusions: These results are consistent with other state-level data. Patients who were diagnosed with cannabis-polydrug poisoning, compared to cannabis alone poisoning, had greater odds of hospital admission and cardiac complications, and longer length of hospital stays.Scientific Significance:The health risks of cannabinoid use must be more broadly recognized, while timely and accurate data need to be shared to guide policies on cannabis access. Future research on cannabinoid poisoning should consider the involvement of other psychoactive drugs.