Recent advances in colorimetry/fluorimetry-based dual-modal sensing technologies
Recent advances in colorimetry/fluorimetry-based dual-modal sensing technologies
复制标题
基于比色法/荧光法的双模态传感技术的最新进展
DOI：
10.1016/j.bios.2021.113386
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发表时间：
2021-06-10
影响因子：
12.6
通讯作者：
Xiong, Yonghua
中科院分区：
文献类型：
--
作者：
Zhou, Yaofeng;Huang, Xiaolin;Xiong, Yonghua
针对日益增长的传感技术需求，提出了将两种信号转导通道结合为一种方法的双峰传感技术，并引起了广泛关注。两种传感信号的集成不仅提高了分析效率，减少了假设，而且提高了分析性能，扩大了检测线性范围，提高了精度，增强了应用灵活性。开发双峰传感器的两个最受欢迎的输出信号是比色和荧光信号，因为它们在护理点应用和实时敏感传感方面具有突出的优点。由于材料化学和纳米技术的快速发展，近十年来，基于比色/荧光信号的双峰传感技术取得了巨大进展。由于两种输出信号的互补和协同效应，新的传感策略为疾病诊断、环境监测和食品安全等各种应用开辟了广阔的途径。在这篇最新的综述中，我们全面总结了不同类型的比色/荧光双峰传感方法，重点介绍了近5年来有代表性的研究，深入研究了它们的传感方法，特别是信号转导系统的工作原理。在此基础上，讨论了该研究领域面临的挑战和进一步发展的前景。
Tailored to the increasing demands for sensing technologies, the fabrication of dual-modal sensing technologies through combining two signal transduction channels into one method has been proposed and drawn considerable attention. The integration of two sensing signals not only promotes the analytical efficiency with reduced assumption, but also improves the analytical performances with enlarged detection linear range, enhanced accuracy, and boosted application flexibility. The two top-rated output signals for developing dual-modal sensors are colorimetric and fluorescent signals because of their outstanding merits for point of care applications and real-time sensitive sensing. Given the rapid development of material chemistry and nanotechnology, the recent decade has witnessed great advance in colorimetric/fluorimetric signal based dual-modal sensing technologies. The new sensing strategy leads to a broad avenue for various applications in disease diagnosis, environmental monitoring and food safety because of the complementary and synergistic effects of the two output signals. In this state-of-the-art review, we comprehensively summarize different types of colorimetric/fluorimetric dual modal sensing methods by highlighting representative research in the last 5 years, digging into their sensing methodologies, particularly the working principles of the signal transduction systems. Then, the challenges and future prospects for boosting further development of this research field are discussed.