Diagnostic stability in very young children with autism spectrum disorders
Diagnostic stability in very young children with autism spectrum disorders
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DOI：
10.1007/s10803-007-0427-8
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发表时间：
2008-04-01
影响因子：
3.9
通讯作者：
Fein, Deborah
中科院分区：
文献类型：
--
作者：
Kleinman, Jamie M.;Ventola, Pamela E.;Fein, Deborah
自闭症谱系障碍（ASD）的诊断在很小的孩子可能会被推迟，由于怀疑的有效性。在这项研究中，77名儿童在16至35个月以及42至82个月之间接受了诊断和发育评估。基于临床判断、儿童孤独症评定量表和孤独症诊断观察表的诊断随时间推移而稳定。使用自闭症诊断访谈进行的诊断略不稳定。根据临床判断，15名儿童（19%）在第二次评估时脱离了自闭症谱系;没有一名儿童进入谱系。结果表明，在2岁时诊断的诊断稳定性在可接受的水平。频谱外的运动可能反映了基于2岁时的成熟，干预或过度诊断的真正改善。
Autism Spectrum Disorders (ASD) diagnosis in very young children may be delayed due to doubts about validity. In this study, 77 children received a diagnostic and developmental evaluation between 16 and 35 months and also between 42 and 82 months. Diagnoses based on clinical judgment, Childhood Autism Rating Scale, and the Autism Diagnostic Observation Schedule were stable over time. Diagnoses made using the Autism Diagnostic Interview were slightly less stable. According to clinical judgment, 15 children (19%) moved off the autism spectrum by the second evaluation; none moved onto the spectrum. Results indicate diagnostic stability at acceptable levels for diagnoses made at age 2. Movement off the spectrum may reflect true improvement based on maturation, intervention, or over-diagnosis at age 2.