Extinction treatment in multiple contexts attenuates ABC renewal in humans
Extinction treatment in multiple contexts attenuates ABC renewal in humans
复制标题
DOI：
10.1016/j.brat.2012.06.003
复制
发表时间：
2012-10-01
影响因子：
4.1
通讯作者：
Boschen, Mark J.
中科院分区：
文献类型：
--
作者：
Balooch, Siavash Bandarian;Neumann, David L.;Boschen, Mark J.
更新换代被认为是暴露治疗后恐惧回归的潜在机制之一。ABC更新在临床上比ABA更新更相关，但它是一种较弱的更新形式，提示在多种情况下进行消退治疗可能足以减弱ABC更新。使用自我报告的震惊和惊吓眨眼反应的预期，目前的研究考察了在多个背景下进行消退治疗对ABC恐惧更新的影响。参与者(N=68)在一个情境(A)中接受条件刺激(CS)和无条件刺激(US)配对，然后在另一个情境(B)或三个其他情境(BCD)中进行消退处理(仅有CS呈现)。在新环境(E)中的非强化测试试验导致那些仅在一种环境中接受灭绝的人恢复了已熄灭的条件性行为。然而，对于那些在三种情况下接受灭绝治疗的人来说，更新是减弱的。在与灭绝期间相同的背景下接受测试试验的对照组没有发现更新。为临床医生提供建议，以防止或减轻暴露治疗后的恐惧复发。(C)2012爱思唯尔有限公司。保留所有权利。
Renewal has been implicated as one of the underlying mechanisms in return of fear following exposure therapy. ABC renewal is clinically more relevant than ABA renewal and yet it is a weaker form of renewal, suggesting that conducting extinction treatment in multiple contexts may be sufficient to attenuate ABC renewal. Using self-reported expectancy of shock and startle blink responses the current study examined the effects of conducting extinction treatment in multiple contexts on ABC fear renewal. Participants (N = 68) received conditional stimulus (CS) and unconditional stimulus (US) pairings in one context (A) followed by extinction treatment (CS presentations alone) in either one other context (B) or three other contexts (BCD). Non-reinforced test trials in a novel context (E) resulted in renewal of extinguished conditioned behaviour for those who received extinction in only one context. However, renewal was attenuated for those who received extinction treatment in three contexts. No renewal was found for the control group that received the test trial in the same context as during extinction. Suggestions are provided for clinicians seeking to prevent or attenuate return of fear following exposure therapy. (C) 2012 Elsevier Ltd. All rights reserved.