The Value of Contrast-Enhanced Transrectal Ultrasound in Predicting the Nature of Prostate Diseases and the Gleason Score of Prostate Cancer by a Subjective Blood Flow Grading Scale
The Value of Contrast-Enhanced Transrectal Ultrasound in Predicting the Nature of Prostate Diseases and the Gleason Score of Prostate Cancer by a Subjective Blood Flow Grading Scale
复制标题
经直肠造影超声对前列腺疾病性质及主观血流分级量表格里森评分预测的价值
DOI：
10.1159/000327988
复制
发表时间：
2011-01-01
影响因子：
1.6
通讯作者：
Chen, Wei
中科院分区：
文献类型：
--
作者：
Zhao, Hong Wei;Luo, Jun Hang;Chen, Wei
Objectives: To investigate the value of contrast-enhanced transrectal ultrasound (CETRUS) in predicting the nature of prostate diseases and prostate cancer Gleason score. Methods: 106 patients suspected of prostate cancer were evaluated with CETRUS followed by systematic biopsy. Prostate blood flow of CETRUS was graded using a subjective 5-point scale. The relationships between ultrasound findings and biopsy outcomes, as well as prostate cancer Gleason score were analyzed. Receiver operating characteristic (ROC) analysis was performed to evaluate the diagnostic performance of CETRUS. Results: Biopsy revealed prostate cancer in 43 of 106 patients. The proportions of malignant histology in the groups with CETRUS scores of 1–5 were 0% (0/10), 8.3% (2/24), 31.7% (13/41), 88.9% (16/18) and 92.3% (12/13), respectively. The rate of prostate cancer with a Gleason score ≧7 in the groups with a CETRUS score of 2–5 were 0% (0/2), 15.4% (2/13), 37.5% (6/16) and 91.7% (11/12), respectively. The blood flow grading scale correlated with pathological outcomes and Gleason score significantly (r = 0.66, p < 0.001; and r = 0.61, p < 0.001, respectively). ROC analysis showed the area under the ROC curve to be 0.87. Conclusions: CETRUS-based blood flow grading scale is a reliable tool for predicting the pathological outcome of prostate diseases and prostate cancer Gleason score noninvasively.
