Is Broca's Area Part of a Basal Ganglia Thalamocortical Circuit?
Is Broca's Area Part of a Basal Ganglia Thalamocortical Circuit?
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DOI：
10.1016/s0010-9452(08)70382-4
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发表时间：
2006-12
期刊：
影响因子：
3.6
通讯作者：
M. Ullman
中科院分区：
文献类型：
--
作者：
M. Ullman
构成布罗卡区的皮质并不是孤立存在的。相反，像其他皮质区域一样，布罗卡区与其他大脑结构相连，这些结构可能发挥着密切相关的功能作用。这篇论文的重点是基底神经节，一组皮质下结构，通过地形组织的“通道”通过丘脑投射到不同的额叶区域。据推测，基底神经节投射到布罗卡区。该电路还被设置为包含至少两个通道。一个通道可以被描述为辅助程序性记忆，而另一个通道则是从陈述性记忆中提取知识的基础。这些假说得到了解剖学和功能学证据的支持。进一步调查的影响和问题进行了讨论。
The cortex constituting Broca's area does not exist in isolation. Rather, like other cortical regions, Broca's area is connected to other brain structures, which likely play closely related functional roles. This paper focuses on the basal ganglia, a set of subcortical structures that project through topographically organized “channels” via the thalamus to different frontal regions. It is hypothesized that the basal ganglia project to Broca's area. This circuitry is further posited to encompass at least two channels. One channel can be characterized as subserving procedural memory, while the other underlies the retrieval of knowledge from declarative memory. These hypotheses are supported by both anatomical and functional evidence. Implications and issues for further investigation are discussed.