Poecillastrin D:: A new cytotoxin of the chondropsin class from marine sponge Jaspis serpentina
Poecillastrin D:: A new cytotoxin of the chondropsin class from marine sponge Jaspis serpentina
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DOI：
10.1271/bbb.70293
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发表时间：
2007-11-01
影响因子：
1.6
通讯作者：
Matsunaga, Shigeki
中科院分区：
文献类型：
--
作者：
Takemoto, Daisaku;Takekawa, Yoshihiko;Matsunaga, Shigeki
Poecillastrin D（2）与Poecillastrin C（1）一起从深海海绵Japsis serpentina中分离得到。通过光谱方法确定其结构为大环内酯内酰胺。这些化合物显示出对各种肿瘤细胞系的有效细胞毒性。
Poecillastrin D (2) was isolated together with poecillastrin C (1) from the deep sea sponge, Japsis serpentina. Its structure was elucidated to be that of a macrolide lactam by spectroscopic methods. These compounds showed potent cytotoxicity against various tumor cell lines.