EPILEPTIC ELECTROENCEPHALOGRAPHIC ABNORMALITIES AND DEVELOPMENTAL DYSPHASIAS - A STUDY OF 32 PATIENTS
EPILEPTIC ELECTROENCEPHALOGRAPHIC ABNORMALITIES AND DEVELOPMENTAL DYSPHASIAS - A STUDY OF 32 PATIENTS
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DOI：
10.1016/s0387-7604(12)80233-6
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发表时间：
1992-07-01
影响因子：
1.7
通讯作者：
BILLIARD, M
中科院分区：
文献类型：
--
作者：
ECHENNE, B;CHEMINAL, R;BILLIARD, M
本文分析了32例先天性言语障碍患者的严重发育性言语障碍与癫痫的关系。平均年龄为8岁2个月; 32例中有19例从未发作过; 9例偶尔发作; 4例癫痫发作。32例中22例重复标准EEG正常，但10例（其中2例从未发作）显示癫痫发作间期放电。在睡眠剥夺后的长时间脑电图中，32例病例中有13例观察到癫痫异常（其中4例从未发生过癫痫发作）。整体夜间睡眠记录显示32例中有30例癫痫异常（其中17例从未发作）。癫痫发作间期异常的强度和方面在同一患者从一个检查到另一个变化很大。发育性失语儿童脑电图异常的发生率高于预期，特别是在夜间记录期间。在大多数情况下，语言障碍的病理生理学可能与Landau-Kleffner综合征相同。
The relationships between severe developmental dysphasias and epilepsy were analysed in 32 patients with congenital dysphasias. The mean age was 8 years 2 months; 19 of 32 had never had seizures; 9 had had occasional seizures; 4 were epileptic. Twenty-two of 32 had normal repeated standard EEGs, but 10 (2 of which never had seizures) showed epileptic interictal discharges. During prolonged EEG after sleep deprivation, epileptic abnormalities were observed in 13 of the 32 cases (4 of which never had seizures). The overall night sleep recordings showed epileptic abnormalities in 30 of the 32 cases (17 of which had never had seizures). The epileptic interictal abnormalities varied considerably in intensity and aspect in the same patient from one examination to another. Developmentally aphasic children show a higher incidence of abnormal EEG than expected, particularly during overall night recordings. In most cases, the physiopathology of the language disturbance might be identical to that in Landau-Kleffner syndrome.