Determination of Dinotefuran and Its Metabolites in Orange Pulp, Orange Peel, and Whole Orange Using Liquid Chromatography-Tandem Mass Spectrometry
Determination of Dinotefuran and Its Metabolites in Orange Pulp, Orange Peel, and Whole Orange Using Liquid Chromatography-Tandem Mass Spectrometry
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液相色谱-串联质谱法测定橙果肉、橙皮和全橙中呋虫胺及其代谢物
DOI：
10.5740/jaoacint.16-0424
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发表时间：
2017-09-01
影响因子：
1.6
通讯作者：
Hu, Deyu
中科院分区：
文献类型：
--
作者：
Yang, Zaihui;Zhang, Kankan;Hu, Deyu
橙色基质（橙色果肉，橙皮和全橙色）中Dinotefuran和代谢物残基的极性特征的测定很困难。因此，本研究的目的是开发一种提取方法，用于通过使用串联质谱法（LC-MS/MS）的液相色谱法（LC-MS/MS）在橙子中测定Dinotefuran及其代谢产物。观察到橙色基质中所有分析物的基质抑制作用。所提出的方法显示目标分子的线性（R-2> = 0.9856）令人满意。 LOD为0.03-0.10 mg/kg，而Dinotefuran及其代谢物的LOQ为0.08-0.40 mg/kg。 RSD值的回收率为79.1-98.7％
Determination of the polar characteristics of dinotefuran and metabolite residues in orange matrixes (orange pulp, orange peel, and whole orange) is difficult. Thus, the purpose of the present study was to develop an extraction method for the determination of dinotefuran and its metabolites in oranges by using liquid chromatography with tandem mass spectrometry (LC-MS/MS). Matrix suppression effects were observed for all analytes in the orange matrixes. The proposed method displayed satisfactory linearity (R-2 >= 0.9856) for the target molecules. The LODs were 0.03-0.10 mg/kg, whereas LOQs were 0.08-0.40 mg/kg for dinotefuran and its metabolites. Recoveries were 79.1-98.7% with RSD values