Prevalence of atopic dermatitis in Japanese elementary schoolchildren
Prevalence of atopic dermatitis in Japanese elementary schoolchildren
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DOI：
10.1111/j.1365-2133.2004.06271.x
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发表时间：
2005-01-01
影响因子：
10.3
通讯作者：
Tamaki, K
中科院分区：
文献类型：
--
作者：
Saeki, H;Iizuka, H;Tamaki, K
背景虽然有几份关于日本学龄儿童特应性皮炎（AD）患病率的调查报告，但还没有全国范围内的研究表明，在学龄儿童的定期健康检查中，皮肤科医生诊断出这种疾病的频率。目的本研究的目的是根据皮肤科医生的定期健康检查，准确评估日本小学生AD的患病率。方法2001/2年，小学生：一年级学生（6-7岁）和六年级学生（年龄11-12岁）由日本八个县（北海道、岩手、东京、岐阜、大坂、广岛、高知和福冈）的皮肤科医生检查。在每个都道府县，从城市和农村地区随机选择公立小学。我们计划对来自八个地区的城市一年级、城市六年级、农村一年级和农村六年级的约700名学童进行检查，共计22 400名儿童（700 X 4 X 8）。AD的诊断是由皮肤科医生根据日本皮肤病协会的疾病critics.Results的点患病率为11.2%的整体（2664 23719），从7.4%（岩手县）到15.0%（福冈县）的8个地区。74%、24%、1.6%和0.3%的受影响者分别属于轻度、中度、重度和极重度群体。小学一年级学生的患病率略高于小学六年级学生（11.8%比10.5%，P < 0.01）。城市和农村地区之间的患病率没有明显差异，或男孩和女孩之间。结论AD在日本小学生的患病率约为10%，四分之三的人受到轻度影响。这是第一个由皮肤科医生对日本小学生进行检查以评估AD频率的全国性研究。
Background Although there have been several reports on the prevalence of atopic dermatitis (AD) in Japanese schoolchildren based on questionnaires, there has been no nation-wide study of the frequency of this condition diagnosed by dermatologists in regular health check-ups of schoolchildren. Objectives The objective of this work was to evaluate precisely the prevalence of AD in elementary schoolchildren in Japan based on regular health check-ups by dermatologists.Methods In 2001/2, elementary schoolchildren: first graders (age 6-7 years) and sixth graders (age 11-12 years) were examined by dermatologists in eight prefectures of Japan (Hokkaido, Iwate, Tokyo, Gifu, Osaka, Hiroshima, Kochi and Fukuoka). In each prefecture, public elementary schools were randomly selected from urban and rural districts. We planned to examine about 700 schoolchildren in each of urban first, urban sixth, rural first and rural sixth grades from the eight areas, a total of 22 400 children (700 X 4 X 8). AD was diagnosed by the dermatologists based on the Japanese Dermatological Association criteria for the disease.Results The point prevalence of AD was 11.2% overall (2664 of 23 719) ranging from 7.4% (Iwate) to 15.0% (Fukuoka) in the eight areas. Seventy-four per cent, 24%, 1.6% and 0.3% of those afflicted were in the mild, moderate, severe and very severe groups, respectively. Overall, the prevalence of first graders was slightly higher than that of sixth graders (11.8% vs. 10.5%, P < 0.01). There was no apparent difference in prevalence between urban and rural districts, or between boys and girls.Conclusions The prevalence of AD in Japanese elementary schoolchildren was about 10%, three-quarters of those being mildly affected. This is the first nation-wide study made of Japanese elementary schoolchildren examined by dermatologists to evaluate the frequency of AD.