Myosin and kinesin: mother and child reunited.
Myosin and kinesin: mother and child reunited.
复制标题
肌球蛋白和驱动蛋白：母亲和孩子团聚。
DOI：
10.1016/s1074-5521(96)90142-8
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发表时间：
1996
影响因子：
--
通讯作者：
Hackney,DD
中科院分区：
文献类型：
--
作者：
Hackney,DD
最近的解决方案的驱动蛋白马达域的晶体结构揭示了惊人的相似之处的核心区域的肌球蛋白马达域，这意味着这两个电机之间的强大的进化关系。然而，要完全理解运动性产生的方式，需要额外的结构信息，这可能解释这两种马达如何适应它们根本不同的线性底物，F-肌动蛋白和微管。
The recent solution of the crystal structure of the kinesin motor domain reveals striking similarities to the core region of the myosin motor domain, implying a strong evolutionary relationship between these two motors. However, a complete understanding of the way that motility is generated will require additional structural information, which may explain how the two motors have adapted to their fundamentally different linear substrates, F-actin and microtubules.