Epidural nonsteroidal antiinflammatory drugs for cancer pain

Epidural nonsteroidal antiinflammatory drugs for cancer pain
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DOI:
10.1097/00000539-199801000-00023
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发表时间:
1998-01-01
影响因子:
5.7
通讯作者:
Pereira, NL
Pereira, NL
中科院分区:
医学2区
文献类型:
--
作者:
Lauretti, GR;Reis, MP;Pereira, NL

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Several reports have suggested a spinal site of action for NSAIDS (3-7) and synergy with spinal morphine (5). However, appropriate preclinical toxicity testing has not been performed for any commercially available NSAID, and intraspinal application is premature (8). We describe two cases in which epidural NSAIDS were administered by our ambulatory cancer patients without our initial knowledge or approval.