ACTIVATION AND ROLE OF NATURAL-KILLER CELLS IN VIRUS-INFECTIONS
ACTIVATION AND ROLE OF NATURAL-KILLER CELLS IN VIRUS-INFECTIONS
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DOI：
10.1007/bf02298196
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发表时间：
1982-01-01
影响因子：
5.4
通讯作者：
WELSH, RM
中科院分区：
文献类型：
--
作者：
BIRON, CA;WELSH, RM
自然杀伤细胞可能在病毒感染中发挥重要作用。病毒诱导的干扰素激活这些细胞，使其具有高度细胞毒性，病毒感染也可能影响这些细胞的增殖。非免疫小鼠具有明显的细胞防御机制，其快速溶解植入的病毒感染的细胞。NK细胞参与病毒性疾病的证据进行审查。
Natural killer cells may play a significant role in virus infections. Virus-induced interferon activates these cells to become highly cytotoxic, and viral infections may also affect the proliferation of such cells. Non-immune mice have an apparently cellular defense mechanism which rapidly lyses implanted virus-infected cells. The evidence for NK cell involvement in viral disease is reviewed.